Sterile water heat exchangers for Water-for-Injection (WFI) are an integral part of the pharmaceutical and biotechnological industries. WFI is sterile water intended for injection into the body and must be non-pyrogenic, free of bacteriostats, antimicrobial agents, or added buffers. Heat exchangers used in WFI production serve to vaporize the water in multiple vaporization columns. Companies like Southwest Thermal offer plate and frame exchangers made of 304 or 316 stainless steel to meet the high demands of sterile water heat transfer. Additionally, some companies have developed compact modules for point of use cooling in pharmaceutical water systems, providing instant cold or hot WFI availability at the point of use. These heat exchangers are chosen, dimensioned, and built according to the thermal program to be implemented and the quality of the treated water distribution loops.